Among 2,370 US couples seeking fertility treatment, 67% of women and 37% of men took a multivitamin, and at one US academic infertility practice, 93.7% of patients took vitamins and 53.7% took herbal supplements. In October 2026, our research team compiled these and other supplement use figures from four published studies and two sets of US national survey data, covering couples seeking fertility treatment, patients at a US infertility practice, US adults and pregnant women nationwide, and cohorts of women in Australia and Germany.
Dietary supplements are common in the US: national survey data show that 57.6% of adults took one in 2017 to 2018, and women more often than men. Supplements are also one of the first things many people add when they start trying to conceive, and fertility clinics see the same pattern among their patients, with routines that often include multivitamins, folic acid, CoQ10, fish oil, and herbal products.
How many people take them, which ones, and who advises them has been measured in a handful of studies, each with its own population. Our study gathered the main figures in one place and kept each one with its population, so the numbers can be compared without being pooled.
We took the published figures from a 2026 Fertility and Sterility analysis of 2,370 couples in two US cohorts, a 2022 survey of 95 patients at a Colorado academic infertility practice, a 2017 study of 485 Australian women before conception, and a 2026 survey of 254 women in German fertility and pregnancy care. For national context, we added the CDC National Center for Health Statistics figures on supplement use among US adults in 2017 to 2018 and the national survey figures for pregnant and breastfeeding women summarized in the NIH iodine fact sheet.
In the sections below, we break down fertility supplement usage among US adults by sex and age, by population and life stage, among couples seeking fertility treatment, by the link between multivitamins and live birth, at a US infertility practice, by herbal product, by where patients learn about supplements, by what women know about recommended micronutrients, by supplement type before conception, and by who takes supplements before conception.
Summary of Findings
- 67% of women and 37% of men took a multivitamin at the start of follow-up among 2,370 US couples seeking fertility treatment.
- 93.7% of patients at a US academic infertility practice took vitamins and 53.7% took herbal supplements, against 49.0% of all US women aged 20 to 39 who take any supplement.
- Only 7.9% of those infertility patients learned about their supplements from a general health care provider, and patients disclosed 33.3% of their supplements to a provider.
- Female multivitamin use was tied to a 22% higher chance of live birth among the 2,370 couples, an adjusted risk ratio of 1.22, while male use showed no link.
- 72.2% of pregnant women in the US took a dietary supplement in 2011 to 2014 national survey data, but only 17.8% of those supplement users took one with iodine.
Supplement Use Among US Adults by Sex and Age
In the table below, we break down dietary supplement use among US adults from the CDC's National Health and Nutrition Examination Survey, for adults aged 20 to 39, the main reproductive years, and for all adults.
| Measure | Ages 20 to 39 | All Ages 20 and Over |
|---|---|---|
| Women, any supplement in the past 30 days | 49.0% | 63.8% |
| Men, any supplement in the past 30 days | 35.9% | 50.8% |
| Both sexes, multivitamin-mineral | 24.0% | |
| Both sexes, vitamin D | 6.7% | |
| Both sexes, omega-3 fatty acids | 5.4% | |
| Both sexes, vitamin C | 5.2% | |
| Both sexes, botanicals | 5.1% | |
| Both sexes, two supplements | 10.2% | 13.8% |
| Both sexes, three supplements | 4.2% | 7.5% |
| Both sexes, four or more supplements | 6.8% | 13.8% |
| Both sexes, any supplement, 2007 to 2008 | 34.7% | 48.4% |
| Both sexes, any supplement, 2017 to 2018 | 42.5% | 56.1% |
- Women, 20 to 3949.0%
- Men, 20 to 3935.9%
- Women, 60 and over80.2%
- Men, 60 and over67.3%
- All adults57.6%
Our researchers drew three conclusions from the national data:
- We found that about half of US women aged 20 to 39, 49.0%, take a dietary supplement, the baseline against which the fertility figures in this report can be read.
- Our data showed that women in that age group are 13.1 percentage points more likely than men to take a supplement.
- We found that supplement use among adults aged 20 to 39 rose from 34.7% in 2007 to 2008 to 42.5% in 2017 to 2018, and that a multivitamin-mineral is the most common type, at 24.0%.
Supplement Use by Population and Life Stage
In the table below, we line up the share taking supplements in each population our study covers, from women of reproductive age in general to couples and patients in fertility care and women in pregnancy. Each figure keeps its source's own definition.
| Population | Country | Data | People | Measure | Share |
|---|---|---|---|---|---|
| Women aged 20 to 39 | US | NHANES, 2017 to 2018 | National sample | Any supplement, past 30 days | 49.0% |
| Women before conception | Australia | ALSWH, 2009 | 485 | Any supplement | 63% |
| Women before conception, iodine | Australia | ALSWH, 2009 | 485 | Supplement with iodine | 37% |
| Female partners seeking fertility treatment | US | FAZST and IDEAL cohorts | 2,370 couples | Multivitamin | 67% |
| Male partners seeking fertility treatment | US | FAZST and IDEAL cohorts | 2,370 couples | Multivitamin | 37% |
| Patients at an infertility practice, vitamins | US | Survey, 2021 | 95 | Vitamins, current | 93.7% |
| Patients at an infertility practice, herbs | US | Survey, 2021 | 95 | Herbal supplements, current | 53.7% |
| Women in fertility or pregnancy care | Germany | Survey, 2026 | 254 | Any supplement, current | 93.7% |
| Pregnant women | US | NHANES, 2011 to 2014 | National sample | Any supplement | 72.2% |
| Pregnant supplement users, iodine | US | NHANES, 2011 to 2014 | National sample | Supplement with iodine, among users | 17.8% |
| Breastfeeding women | US | NHANES, 2011 to 2014 | National sample | Any supplement | 75% |
| Breastfeeding supplement users, iodine | US | NHANES, 2011 to 2014 | National sample | Supplement with iodine, among users | 19% |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; National Center for Health Statistics, Dietary Supplement Use Among Adults: United States, 2017 to 2018, Data Brief No. 399, February 2021; NIH Office of Dietary Supplements, Iodine Fact Sheet for Health Professionals, updated November 5, 2024; McKenna and colleagues, Nutrients, 2017; Sealy and colleagues, Fertility and Sterility, 2026; Friedman and colleagues, F&S Reports, 2022; Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
- US women, 20 to 3949.0%
- Australian women before conception63%
- US female partners, multivitamin67%
- US pregnant women72.2%
- US breastfeeding women75%
- US infertility practice, vitamins93.7%
- German fertility and pregnancy care93.7%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; National Center for Health Statistics, Dietary Supplement Use Among Adults: United States, 2017 to 2018, Data Brief No. 399, February 2021; NIH Office of Dietary Supplements, Iodine Fact Sheet for Health Professionals, updated November 5, 2024; McKenna and colleagues, Nutrients, 2017; Sealy and colleagues, Fertility and Sterility, 2026; Friedman and colleagues, F&S Reports, 2022; Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
Our team took three findings from the population data:
- We found that supplement use climbs with each step toward pregnancy, from 49.0% of US women aged 20 to 39 to 72.2% of pregnant women and 93.7% of patients at a US infertility practice.
- Our data showed that the female partner in a couple seeking fertility treatment was 1.8 times as likely as the male partner to take a multivitamin.
- We found that iodine lags in every group with a figure: 17.8% of US pregnant supplement users and 19% of breastfeeding users took a supplement with iodine, and 37% of Australian women did before conception.
Supplement Use Among Couples Seeking Fertility Treatment
In the table below, we compare the female and male partners among 2,370 US couples seeking fertility treatment in the FAZST and IDEAL cohorts, which recorded supplement use for both partners at the start of follow-up.
| Measure | Female Partner | Male Partner |
|---|---|---|
| Took a multivitamin at baseline | 67% | 37% |
| Five most common other supplements | Calcium, fish oil, folic acid, vitamin B12, vitamin C | Coenzyme Q10, fish oil, vitamin B12, vitamin C, zinc |
| Adjusted risk ratio for live birth with a multivitamin | 1.22 | 1.00 |
| 95% confidence interval | 1.05 to 1.41 | 0.89 to 1.12 |
| Multivitamin use linked to pregnancy loss | No | No |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Sealy and colleagues, Fertility and Sterility, 2026
- Female partner67%
- Male partner37%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Sealy and colleagues, Fertility and Sterility, 2026
Our researchers drew three conclusions from the couples data:
- We found that women were 1.8 times as likely as men to take a multivitamin at the start of follow-up, a gap of 30 percentage points.
- Our data showed that coenzyme Q10 and zinc appear only on the men's list of common supplements, and calcium and folic acid only on the women's.
- We found that fish oil, vitamin B12, and vitamin C were among the five most common supplements for both partners.
Multivitamin Use and Live Birth in Fertility Treatment
In the table below, we list the adjusted risk ratios for live birth that the US couples study reported for each supplement and partner over up to 18 months, with 95% confidence intervals. A risk ratio above 1.0 means a higher chance of live birth among users.
| Supplement and Partner | Adjusted Risk Ratio | 95% Confidence Interval |
|---|---|---|
| Multivitamin, female partner | 1.22 | 1.05 to 1.41 |
| Multivitamin, female partner, no fertility treatment | 1.44 | 1.00 to 2.08 |
| Folic acid, female partner | 1.18 | 0.95 to 1.48 |
| Fish oil, female partner | 1.09 | 0.86 to 1.36 |
| Multivitamin, male partner | 1.00 | 0.89 to 1.12 |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Sealy and colleagues, Fertility and Sterility, 2026
- Multivitamin, female1.22 (1.05 to 1.41)
- Multivitamin, female, no treatment1.44 (1.00 to 2.08)
- Folic acid, female1.18 (0.95 to 1.48)
- Fish oil, female1.09 (0.86 to 1.36)
- Multivitamin, male1.00 (0.89 to 1.12)
Vertical line: a risk ratio of 1.0, meaning no difference
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Sealy and colleagues, Fertility and Sterility, 2026
Our team took three findings from the live birth data:
- We found that only the female multivitamin estimate sits clearly above 1.0, while the intervals for folic acid and fish oil cross it.
- Our data showed that 44% of the couples conceived and 35% had a live birth, and 21% of pregnancies ended in loss, with no link between multivitamin use and loss in either partner.
- We found that supplement use was recorded, not assigned, so the results show an association, not proof that multivitamins caused more births.
Supplement Use at a US Infertility Practice
In the table below, we break down the supplement use, prescription use, and fertility treatments that 95 patients reported in a 2021 survey at a Colorado academic infertility practice.
| Measure | Result |
|---|---|
| Median age | 35 |
| Had used supplements or herbal medicines in the past | 68.4% |
| Currently take vitamins | 93.7% |
| Currently take herbal supplements | 53.7% |
| Median number of supplements per patient | 2 |
| Take prescription medications | 69.5% |
| Treated with IVF | 26.3% |
| Treated with IUI | 24.2% |
| Treated with letrozole | 16.8% |
| Treated with clomiphene citrate | 11.6% |
| Treated with hormonal injections | 9.5% |
| Supplements disclosed to a provider | 33.3% |
| Moderate-risk supplement and drug interactions identified | 41 |
| Interactions involving infertility treatment | 12 |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Friedman and colleagues, F&S Reports, 2022
- Vitamins, current93.7%
- Prescription medications69.5%
- Supplements or herbs, in the past68.4%
- Herbal supplements, current53.7%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Friedman and colleagues, F&S Reports, 2022
Our researchers drew three conclusions from the practice survey:
- We found that almost every patient took vitamins, and more than half added at least one herbal product.
- Our data showed that 69.5% of the patients also took prescription medications, and the authors identified 41 moderate-risk interactions between the supplements and drugs reported, 12 of them involving infertility treatment.
- We found that patients disclosed only a third of their supplements to a provider, so a clinic may not see much of what its patients take.
The Most Common Herbal Supplements Among Infertility Patients
In the table below, we list the herbal products the practice's patients used most often, the share of the 95 patients using each, and whether the study's interaction table flagged an interaction with letrozole, an ovulation drug used in fertility treatment.
| Herbal Product | Patients Using | Share of Patients | Letrozole Interaction Flagged |
|---|---|---|---|
| Green tea | 14 | 14.7% | No |
| Chamomile | 12 | 12.6% | Yes |
| Peppermint | 9 | 9.5% | Yes |
| Turmeric | 8 | 8.4% | No |
| Elderberry | 7 | 7.4% | No |
| Ginger | 7 | 7.4% | No |
| Maca | 6 | 6.3% | No |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Friedman and colleagues, F&S Reports, 2022
- Green tea14.7%
- Chamomile12.6%
- Peppermint9.5%
- Turmeric8.4%
- Elderberry7.4%
- Ginger7.4%
- Maca6.3%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Friedman and colleagues, F&S Reports, 2022
Our team took three findings from the herbal data:
- We found that the most common herbal products were everyday teas and spices, led by green tea, and tea was the most common form, at 42.3% of herbal use against 23.8% for pills and capsules.
- Our data showed that maca was the herb most often taken specifically for fertility, by five patients, and that fertility, at 15.0%, ranked behind general health, at 24.5%, and immune support, at 16.2%, among reasons for herbal use.
- We found that two of the seven most common herbs, chamomile and peppermint, carry a flagged interaction with letrozole, and the study flags chasteberry, which three patients took for fertility, as possibly unsafe in pregnancy.
Where Patients Learn About Supplements
In the table below, we compare where patients learn about supplements in two studies: where patients at the US infertility practice learned about their herbal products, and the primary source of supplement information for women in German fertility and pregnancy care.
| Source | US Infertility Practice, 2021 | German Fertility and Pregnancy Care, 2026 |
|---|---|---|
| Friends and family | 43.9% | |
| Internet | 28.0% | 33.9% |
| Alternative medicine providers | 20.2% | |
| General health care providers | 7.9% | |
| Gynecologist | 37.8% | |
| Other sources | 27.6% | |
| No information received | 0.8% |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Friedman and colleagues, F&S Reports, 2022; NutraIngredients, report on the Friedman study, April 17, 2023; Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
- Friends and family43.9%
- Internet28.0%
- Alternative medicine providers20.2%
- General health care providers7.9%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; NutraIngredients, report on the Friedman study, April 17, 2023
Our researchers drew three conclusions from the information source data:
- We found that friends and family were the leading source at the US practice, more than five times as common as a general health care provider.
- Our data showed that the internet was a leading source in both studies, at 28.0% in the US and 33.9% in Germany.
- We found that in the German study, which asked for the primary source, a gynecologist led at 37.8%, and only 0.8% of women said they had received no information.
What Women Know About Recommended Micronutrients
In the table below, we break down which of six recommended micronutrients 254 women in German fertility and pregnancy care knew before receiving information, alongside the range of each nutrient across the multiple micronutrient supplements they reported taking.
| Micronutrient | Recommended Daily Amount Listed in the Study | Women Who Knew It | Lowest in Supplements Taken | Highest | Average |
|---|---|---|---|---|---|
| Folic acid | 400 mcg added | 89.9% | 400 mcg | 1,000 mcg | 590 mcg |
| Iodine | 100 to 150 mcg added | 25.2% | 100 mcg | 150 mcg | 146 mcg |
| Iron | 30 mg | 24.4% | 5 mg | 454 mg | 36 mg |
| Vitamin D | 800 IU if deficient | 21.3% | 200 IU | 2,000 IU | 725 IU |
| Vitamin B12 | 4.5 mcg | 19.3% | 2.6 mcg | 60 mcg | 7.9 mcg |
| Choline | 480 mg | 1.6% | 100 mg | 130 mg | 121 mg |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
- Folic acid89.9%
- Iodine25.2%
- Iron24.4%
- Vitamin D21.3%
- Vitamin B1219.3%
- Choline1.6%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
Our team took three findings from the knowledge data:
- We found that 89.9% of the women knew folic acid was a recommended micronutrient, but no other nutrient reached 26%, and only 1.6% knew choline was one.
- Our data showed that the multiple micronutrient supplements the women took contained 100 to 130 mg of choline, about a quarter of the 480 mg adequate intake the study lists.
- We found that iron varied most, from 5 mg to 454 mg across products against a 30 mg recommended amount, which the authors flag as a risk of over- or underdosage.
Supplement Types Taken Before Conception
In the table below, we list the supplement types taken by 485 Australian women surveyed before conception in 2009, from the Australian Longitudinal Study on Women's Health, which breaks use down by type.
| Supplement Type | Women | Share of Women |
|---|---|---|
| Any supplement | 305 | 63% |
| Any supplement containing folic acid | 51% | |
| Any supplement containing iodine | 37% | |
| Multiple micronutrient | 212 | 43.7% |
| Any single-nutrient supplement | 167 | 34.4% |
| Folic acid alone | 62 | 12.8% |
| Omega-3 or fish oil | 52 | 10.7% |
| Vitamin C | 33 | 6.8% |
| B vitamins | 18 | 3.7% |
| Iron | 15 | 3.1% |
| Calcium | 14 | 2.9% |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; McKenna and colleagues, Nutrients, 2017
- Multiple micronutrient43.7%
- Folic acid alone12.8%
- Omega-3 or fish oil10.7%
- Vitamin C6.8%
- B vitamins3.7%
- Iron3.1%
- Calcium2.9%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; McKenna and colleagues, Nutrients, 2017
Our researchers drew three conclusions from the supplement type data:
- We found that multiple micronutrient products were the most common type, taken by 43.7% of the women, more than three times the share taking folic acid alone.
- Our data showed that 51% took a supplement containing folic acid before conception, so about half were not getting folic acid from a supplement.
- We found that omega-3 or fish oil was the most common single-nutrient product after folic acid, at 10.7%.
Who Takes Supplements Before Conception
In the table below, we calculated the share of the Australian women in each group who took a supplement, from the study's counts of women who did and did not supplement.
| Group | Took a Supplement | Did Not | Share Taking a Supplement |
|---|---|---|---|
| Trying to conceive | 149 | 42 | 78.0% |
| Not trying to conceive | 159 | 137 | 53.7% |
| No previous children | 107 | 37 | 74.3% |
| One previous child | 139 | 85 | 62.1% |
| Two or more previous children | 50 | 58 | 46.3% |
| Born outside Australia | 26 | 6 | 81.3% |
| Born in Australia | 277 | 172 | 61.7% |
| Does not smoke | 288 | 159 | 64.4% |
| Smokes daily | 6 | 11 | 35.3% |
| Household income $130,000 or more | 98 | 45 | 68.5% |
| Household income $37,000 to $129,999 | 169 | 118 | 58.9% |
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; McKenna and colleagues, Nutrients, 2017
- Born outside Australia81.3%
- Trying to conceive78.0%
- No previous children74.3%
- Not trying to conceive53.7%
- Two or more previous children46.3%
- Smokes daily35.3%
Source: Fertility Supplement Index analysis of published supplement use studies, October 2026; McKenna and colleagues, Nutrients, 2017
Our team took three findings from the group data:
- We found that women trying to conceive were far more likely to take a supplement, 78.0% against 53.7% of women who were not trying.
- Our data showed that use fell with each previous child, from 74.3% of women with none to 46.3% of women with two or more.
- We found that the income gap, 68.5% against 58.9%, was not statistically significant in the study, while women who smoked daily were the least likely group to supplement, at 35.3%.
What the Usage Numbers Mean for Couples Trying to Conceive
Supplements are close to universal among women in fertility care and common among men, but the advice behind them mostly comes from outside the clinic. The gap between what patients take and what they tell their providers carries the clearest practical risk, given the interactions found with infertility drugs.
Across the studies, the pattern holds: use rises as women move toward pregnancy, women take more than men, and herbal products often sit beside standard vitamins. In the US couples data, the clearest link to live birth came from a plain multivitamin for the female partner.
So if you are trying to conceive, bring a full list of what each partner takes, herbs included, to your next appointment.
Sources (8)
- 1.Fertility Supplement Index analysis of published supplement use studies, October 2026
- 2.National Center for Health Statistics, Dietary Supplement Use Among Adults: United States, 2017 to 2018, Data Brief No. 399, February 2021
- 3.Sealy and colleagues, Fertility and Sterility, 2026
- 4.Friedman and colleagues, F&S Reports, 2022
- 5.NutraIngredients, report on the Friedman study, April 17, 2023
- 6.NIH Office of Dietary Supplements, Iodine Fact Sheet for Health Professionals, updated November 5, 2024
- 7.McKenna and colleagues, Nutrients, 2017
- 8.Breuste and colleagues, Archives of Gynecology and Obstetrics, 2026
Methodology
We included published studies that report how many people take supplements while trying to conceive, in fertility care, or in pregnancy, and opened each one on October 29, 2026. US data comes first. Each figure keeps its study's own definition and population, and we did not pool them.
The couples figures come from a secondary analysis of the FAZST and IDEAL cohorts, with supplement use recorded at baseline and live birth tracked for up to 18 months. Risk ratios are as published, adjusted for confounders and weighted for selection bias.
The infertility practice survey ran from January to July 2021. Shares for reasons and information sources are as reported, and the information-source shares come from the NutraIngredients report of the study. Shares of patients using each herb are our calculations from the study's counts, and letrozole interactions are as listed in the study's interaction table.
US adult figures come from NCHS Data Brief No. 399. Figures for all adults in 2007 to 2008 and 2017 to 2018 are age adjusted, and figures for ages 20 to 39 are for that age group. Iodine shares from the 2011 to 2014 national survey data are among supplement users.
The German survey's recommended amounts and supplement dose ranges are as published, for the multiple micronutrient supplements participants reported. The Australian group shares are our calculations from the study's counts of women who did and did not supplement, and the study's group counts do not always sum to its totals.
We calculated products, differences, and ratios from the published values.